agranular orbitofrontal cortex
Acronym: OFCa
The term agranular orbitofrontal cortex (OFCa) refers to the orbital component of the insulo-orbital agranular cortex (IOC) of the human ( Ongur-2003 ) and the macaque ( Carmichael-1994 ). Topologically located entirely on the posterolateral surface of the orbital gyri (ORG) of the frontal lobe (FLB), it is histologically the same as the insular component of IOC, the agranular sector of the insula (INSag). Caudally, it is continuous with the INSag; rostrally It is bordered by area 13 and area 47.
      The OFCa is composed of four parts, which are differentiated by staining patterns for a number of different neurochemicals: area Iam, area Iai, and area Iapm in the human and the same in the macaque, except that, in the macaque, the fourth subdivision is area Iapl.
      While it has no topological equivalent in the smooth cortex of the rat ( Swanson-2004 ) or mouse ( Dong-2004 ), the OFCa of primates is equivalent histologically to the rodent's agranular insular cortex (INSag). The INSag of rodents is located rostrally on the ventrolateral surface of the cerebral cortex (CTX), dorsal to the piriform cortex (PIR) and ventral to the gustatory cortex (G1) and visceral sensory cortex. Updated 1 Oct 2024.

Also known as: No other name for this structure has appeared in PubMed.NeuroNames ID : 3501


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